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Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes

STUDY QUESTION: Is the postovulatory aging-dependent differential decrease of mRNAs and polyadenylation of mRNAs coded by maternal effect genes associated with altered abundance and distribution of maternal effect and RNA-binding proteins (MSY2)? SUMMARY ANSWER: Postovulatory aging results in differ...

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Detalhes bibliográficos
Publicado no:Hum Reprod
Main Authors: Trapphoff, T., Heiligentag, M., Dankert, D., Demond, H., Deutsch, D., Fröhlich, T., Arnold, G.J., Grümmer, R., Horsthemke, B., Eichenlaub-Ritter, U.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853592/
https://ncbi.nlm.nih.gov/pubmed/26577303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dev279
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