Homeostatic Expansion of CD4(+) T Cells Promotes Cortical and Trabecular Bone Loss, Whereas CD8(+) T Cells Induce Trabecular Bone Loss Only

BACKGROUND: Bone loss occurs in human immunodeficiency virus (HIV) infection but paradoxically is intensified by HIV-associated antiretroviral therapy (ART), resulting in an increased fracture incidence that is largely independent of ART regimen. Inflammation in the bone microenvironment associated...

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Vydáno v:J Infect Dis
Hlavní autoři: Weitzmann, M Neale, Vikulina, Tatyana, Roser-Page, Susanne, Yamaguchi, Masayoshi, Ofotokun, Ighovwerha
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853557/
https://ncbi.nlm.nih.gov/pubmed/28968828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix444
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