A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defense

Acute respiratory virus infections predispose the cystic fibrosis (CF) lung to chronic bacterial colonization, which contributes to high mortality. For reasons unknown, respiratory virus infections have a prolonged duration in CF. Here, we demonstrate that mice carrying the most frequent cystic fibr...

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Bibliographic Details
Published in:	J Infect Dis
Main Authors:	Svedin, Emma, Utorova, Renata, Hühn, Michael H, Larsson, Pär G, Stone, Virginia M, Garimella, Manasa, Lind, Katharina, Hägglöf, Thomas, Pincikova, Terezia, Laitinen, Olli H, McInerney, Gerald M, Scholte, Bob, Hjelte, Lena, Karlsson, Mikael C I, Flodström-Tullberg, Malin
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2017
Subjects:	Major Articles and Brief Reports
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5853514/ https://ncbi.nlm.nih.gov/pubmed/28968805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix474
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A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defense

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