Lower Levels of Cervicovaginal Tryptophan Are Associated With Natural Clearance of Chlamydia in Women

Chlamydia trachomatis (Ct) infection causes significant morbidity. In vitro studies demonstrate that Ct growth inhibition occurs by interferon-gamma (IFN-γ)–mediated depletion of intracellular tryptophan, and some Ct strains utilize extracellular indole to restore tryptophan levels. Whether tryptoph...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Jordan, Stephen J., Olson, Kristin M., Barnes, Stephen, Wilson, Landon S., Berryhill, Taylor F., Bakshi, Rakesh, Brown, LaDraka’ T., Press, Christen G., Geisler, William M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853498/
https://ncbi.nlm.nih.gov/pubmed/28520912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix240
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