Intestinal Immune Responses to Type 2 Oral Polio Vaccine (OPV) Challenge in Infants Previously Immunized With Bivalent OPV and Either High-Dose or Standard Inactivated Polio Vaccine

BACKGROUND: The impact of inactivated polio vaccines (IPVs) on intestinal mucosal immune responses to live poliovirus is poorly understood. METHODS: In a 2014 phase 2 clinical trial, Panamanian infants were immunized at 6, 10, and 14 weeks of age with bivalent oral polio vaccine (bOPV) and randomize...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Brickley, Elizabeth B, Strauch, Carolyn B, Wieland-Alter, Wendy F, Connor, Ruth I, Lin, Shu, Weiner, Joshua A, Ackerman, Margaret E, Arita, Minetaro, Oberste, M Steven, Weldon, William C, Sáez-Llorens, Xavier, Bandyopadhyay, Ananda S, Wright, Peter F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853416/
https://ncbi.nlm.nih.gov/pubmed/29304199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix556
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