Comparative Genomic Analysis and In Vivo Modeling of Streptococcus pneumoniae ST3081 and ST618 Isolates Reveal Key Genetic and Phenotypic Differences Contributing to Clonal Replacement of Serotype 1 in The Gambia

Streptococcus pneumoniae serotype 1 is one of the leading causes of invasive pneumococcal disease (IPD) in West Africa, with ST618 being the dominant cause of IPD in The Gambia. Recently however, a rare example of clonal replacement was observed, where the ST3081 clone of serotype 1 replaced the pre...

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發表在:J Infect Dis
Main Authors: Bricio-Moreno, Laura, Ebruke, Chinelo, Chaguza, Chrispin, Cornick, Jennifer, Kwambana-Adams, Brenda, Yang, Marie, Mackenzie, Grant, Wren, Brendan W, Everett, Dean, Antonio, Martin, Kadioglu, Aras
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
主題:
Major Articles and Brief Reports
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853340/
https://ncbi.nlm.nih.gov/pubmed/28968897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix472
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