Assessing the Spectrum of Germline Variation in Fanconi Anemia Genes among Patients with Head and Neck Carcinoma before Age 50

Patients with Fanconi anemia (FA) have increased risk for head and neck squamous cell carcinoma (HNSCC). We sought to determine the prevalence of undiagnosed FA and FA carriers in patients with HNSCC and an age cutoff for FA genetic screening. Screening germline DNA from 417 HNSCC patients under age...

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Publicado no:Cancer
Main Authors: Chandrasekharappa, Settara C., Chinn, Steven B., Donovan, Frank X., Chowdhury, Naweed I., Kamat, Aparna, Adeyemo, Adebowale A., Thomas, James W., Vemulapalli, Meghana, Hussey, Caroline S., Reid, Holly H., Mullikin, James C., Wei, Qingyi, Sturgis, Erich M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853120/
https://ncbi.nlm.nih.gov/pubmed/28678401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30802
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