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The Longitudinal Trajectory of Default Mode Network Connectivity in Healthy Older Adults Varies As a Function of Age and Is Associated with Changes in Episodic Memory and Processing Speed

The default mode network (DMN) supports memory functioning and may be sensitive to preclinical Alzheimer's pathology. Little is known, however, about the longitudinal trajectory of this network's intrinsic functional connectivity (FC). In this study, we evaluated longitudinal FC in 111 cog...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Staffaroni, Adam M., Brown, Jesse A., Casaletto, Kaitlin B., Elahi, Fanny M., Deng, Jersey, Neuhaus, John, Cobigo, Yann, Mumford, Paige S., Walters, Samantha, Saloner, Rowan, Karydas, Anna, Coppola, Giovanni, Rosen, Howie J., Miller, Bruce L., Seeley, William W., Kramer, Joel H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852659/
https://ncbi.nlm.nih.gov/pubmed/29440553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3067-17.2018
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