PRMT5 promotes cell proliferation by inhibiting BTG2 expression via the ERK signaling pathway in hepatocellular carcinoma

Increasing evidence suggests that PRMT5, a protein arginine methyltransferase, has roles in cell growth regulation and cancer development. However, the role of PRMT5 in hepatocellular carcinoma (HCC) progression remains unclear. Here, we showed that PRMT5 expression was frequently upregulated in HCC...

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Dades bibliogràfiques
Publicat a:Cancer Med
Autors principals: Jiang, Hai, Zhu, Yue, Zhou, Zhenyu, Xu, Junyang, Jin, Shaowen, Xu, Kang, Zhang, Heyun, Sun, Qing, Wang, Jie, Xu, Junyao
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Cancer Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852340/
https://ncbi.nlm.nih.gov/pubmed/29441724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1360
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