Imaging single DNA molecules for high precision NIPT

Cell-free DNA analysis is becoming adopted for first line aneuploidy screening, however for most healthcare programs, cost and workflow complexity is limiting adoption of the test. We report a novel cost effective method, the Vanadis NIPT assay, designed for high precision digitally-enabled measurem...

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Udgivet i:Sci Rep
Main Authors: Dahl, Fredrik, Ericsson, Olle, Karlberg, Olof, Karlsson, Filip, Howell, Mathias, Persson, Fredrik, Roos, Fredrik, Stenberg, Johan, Ahola, Tarja, Alftrén, Ida, Andersson, Björn, Barkenäs, Emelie, Brandner, Birgit, Dahlberg, Jenny, Elfman, Sara, Eriksson, Magnus, Forsgren, Per-Ola, Francois, Niels, Gousseva, Anna, Hakamali, Faizan, Janfalk-Carlsson, Åsa, Johansson, Henrik, Lundgren, Johanna, Mohsenchian, Atefeh, Olausson, Linus, Olofsson, Simon, Qureshi, Atif, Skarpås, Björn, Sävneby, Anna, Åström, Eva, Öhman, Ove, Westgren, Magnus, Kopp-Kallner, Helena, Fianu-Jonasson, Aino, Syngelaki, Argyro, Nicolaides, Kypros
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852104/
https://ncbi.nlm.nih.gov/pubmed/29540801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22606-0
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