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Impact of sirtuin-1 expression on H3K56 acetylation and oxidative stress: a double-blind randomized controlled trial with resveratrol supplementation

AIMS: Sirtuin-1 (SIRT-1) down-regulation in type 2 diabetes mellitus (T2DM) has been associated with epigenetic markers of oxidative stress. We herein aim to evaluate whether an increase in SIRT-1 expression affects histone 3 acetylation at the 56 lysine residue (H3K56ac) in T2DM patients randomly s...

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Detalhes bibliográficos
Publicado no:Acta Diabetol
Main Authors: Bo, Simona, Togliatto, Gabriele, Gambino, Roberto, Ponzo, Valentina, Lombardo, Giusy, Rosato, Rosalba, Cassader, Maurizio, Brizzi, Maria Felice
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Milan 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851693/
https://ncbi.nlm.nih.gov/pubmed/29330620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00592-017-1097-4
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