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Genetic Pathogenesis of Hypertrophic and Dilated Cardiomyopathy

Sarcomere cardiomyopathies are genetic diseases that perturb contractile function and lead to dilated or hypertrophic myocardial remodeling. Identification of preclinical mutation carriers has yielded insights into the earliest biomechanical defects that link pathogenic variants to cardiac dysfuncti...

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Detalhes bibliográficos
Publicado no:Heart Fail Clin
Main Authors: Garfinkel, Amanda C., Seidman, Jonathan G., Seidman, Christine E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851453/
https://ncbi.nlm.nih.gov/pubmed/29525643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hfc.2017.12.004
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