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Genetic Pathogenesis of Hypertrophic and Dilated Cardiomyopathy

Sarcomere cardiomyopathies are genetic diseases that perturb contractile function and lead to dilated or hypertrophic myocardial remodeling. Identification of preclinical mutation carriers has yielded insights into the earliest biomechanical defects that link pathogenic variants to cardiac dysfuncti...

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Detalles Bibliográficos
Publicado en:Heart Fail Clin
Autores principales: Garfinkel, Amanda C., Seidman, Jonathan G., Seidman, Christine E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851453/
https://ncbi.nlm.nih.gov/pubmed/29525643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hfc.2017.12.004
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