Caloric restriction lowers endocannabinoid tonus and improves cardiac function in type 2 diabetes

BACKGROUND/OBJECTIVES: Endocannabinoids (ECs) are associated with obesity and ectopic fat accumulation, both of which play a role in the development of cardiovascular disease (CVD) in type 2 diabetes (T2D). The effect of prolonged caloric restriction on ECs in relation to fat distribution and cardia...

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Vydáno v:Nutr Diabetes
Hlavní autoři: van Eyk, Huub J., van Schinkel, Linda D., Kantae, Vasudev, Dronkers, Charlotte E. A., Westenberg, Jos J. M., de Roos, Albert, Lamb, Hildo J., Jukema, J. Wouter, Harms, Amy C., Hankemeier, Thomas, van der Stelt, Mario, Jazet, Ingrid M., Rensen, Patrick C. N., Smit, Johannes W. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851430/
https://ncbi.nlm.nih.gov/pubmed/29343706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41387-017-0016-7
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