ロード中...

Complete correction of hemophilia B phenotype by FIX-Padua skeletal muscle gene therapy in an inhibitor-prone dog model

Skeletal muscle–directed expression of FIX-Padua resulted in complete correction of HB phenotype in an inhibitor-prone dog model. Long-term immune tolerance to FIX is sustained over years upon multiple challenges with recombinant FIX protein in 2 HB models.

保存先:
書誌詳細
出版年:Blood Adv
主要な著者: French, Robert A., Samelson-Jones, Benjamin J., Niemeyer, Glenn P., Lothrop, Clinton D., Merricks, Elizabeth P., Nichols, Timothy C., Arruda, Valder R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851422/
https://ncbi.nlm.nih.gov/pubmed/29500218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017015313
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!