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The process defines the product: what really matters in biosimilar design and production?
Biologic drugs are highly complex molecules produced by living cells through a multistep manufacturing process. The key characteristics of these molecules, known as critical quality attributes (CQAs), can vary based on post-translational modifications that occur in the cellular environment or during...
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| Publicado no: | Rheumatology (Oxford) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5850795/ https://ncbi.nlm.nih.gov/pubmed/28903544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kex278 |
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