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Preconception urinary phthalate concentrations and sperm DNA methylation profiles among men undergoing IVF treatment: a cross-sectional study

STUDY QUESTION: Are preconception phthalate and phthalate replacements associated with sperm differentially methylated regions (DMRs) among men undergoing IVF? SUMMARY ANSWER: Ten phthalate metabolites were associated with 131 sperm DMRs that were enriched in genes related to growth and development,...

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Bibliographic Details
Published in:Hum Reprod
Main Authors: Wu, Haotian, Estill, Molly S, Shershebnev, Alexander, Suvorov, Alexander, Krawetz, Stephen A, Whitcomb, Brian W, Dinnie, Holly, Rahil, Tayyab, Sites, Cynthia K, Pilsner, J Richard
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850785/
https://ncbi.nlm.nih.gov/pubmed/29024969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dex283
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