A Population-Based Assessment of the Impact of 7- and 13-Valent Pneumococcal Conjugate Vaccines on Macrolide-Resistant Invasive Pneumococcal Disease: Emergence and Decline of Streptococcus pneumoniae Serotype 19A (CC320) With Dual Macrolide Resistance Mechanisms

BACKGROUND: Macrolide efflux encoded by mef(E)/mel and ribosomal methylation encoded by erm(B) confer most macrolide resistance in Streptococcus pneumoniae. Introduction of the heptavalent pneumococcal conjugate vaccine (PCV7) in 2000 reduced macrolide-resistant invasive pneumococcal disease (MR-IPD...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Schroeder, Max R, Chancey, Scott T, Thomas, Stephanie, Kuo, Wan-Hsuan, Satola, Sarah W, Farley, Monica M, Stephens, David S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Articles and Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850556/
https://ncbi.nlm.nih.gov/pubmed/28903506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cix446
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