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Dosing Guidance for Intravenous Colistin in Critically Ill Patients

BACKGROUND. Intravenous colistin is difficult to use because plasma concentrations for antibacterial effect overlap those causing nephrotoxicity, and there is large interpatient variability in pharmacokinetics. The aim was to develop dosing algorithms for achievement of a clinically desirable averag...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Nation, Roger L., Garonzik, Samira M., Thamlikitkul, Visanu, Giamarellos-Bourboulis, Evangelos J., Forrest, Alan, Paterson, David L., Li, Jian, Silveira, Fernanda P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850520/
https://ncbi.nlm.nih.gov/pubmed/28011614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciw839
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