T-Helper 17 Cell Cytokine Responses in Lyme Disease Correlate With Borrelia burgdorferi Antibodies During Early Infection and With Autoantibodies Late in the Illness in Patients With Antibiotic-Refractory Lyme Arthritis

BACKGROUND. Control of Lyme disease is attributed predominantly to innate and adaptive T-helper 1 cell (T(H)1) immune responses, whereas the role of T-helper 17 cell (T(H)17) responses is less clear. Here we characterized these inflammatory responses in patients with erythema migrans (EM) or Lyme ar...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Strle, Klemen, Sulka, Katherine B., Pianta, Annalisa, Crowley, Jameson T., Arvikar, Sheila L., Anselmo, Anthony, Sadreyev, Ruslan, Steere, Allen C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850331/
https://ncbi.nlm.nih.gov/pubmed/28077518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cix002
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