Neopterin Counters Vascular Inflammation and Atherosclerosis

BACKGROUND: Neopterin, a metabolite of GTP, is produced by activated macrophages and is abundantly expressed within atherosclerotic lesions in human aorta and carotid and coronary arteries. We aimed to clarify the influence of neopterin on both vascular inflammation and atherosclerosis, as neither e...

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Detalles Bibliográficos
Publicado en:J Am Heart Assoc
Autores principales: Shirai, Remina, Sato, Kengo, Yamashita, Tomoyuki, Yamaguchi, Maho, Okano, Taisuke, Watanabe‐Kominato, Kaho, Watanabe, Rena, Matsuyama, Taka‐aki, Ishibashi‐Ueda, Hatsue, Koba, Shinji, Kobayashi, Youichi, Hirano, Tsutomu, Watanabe, Takuya
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850243/
https://ncbi.nlm.nih.gov/pubmed/29420219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.007359
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