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Dependency of Vaccine Efficacy on Preexposure and Age: A Closer Look at a Tetravalent Dengue Vaccine

BACKGROUND: A recombinant, live-attenuated, tetravalent dengue vaccine (CYD-TDV) was licensed for children aged ≥9 years in a few countries, but the dependence of vaccine efficacy on baseline immunity status and age groups has not been fully characterized. METHODS: Combining the 2 phase 3 trials CYD...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Yang, Yang, Meng, Ya, Halloran, M Elizabeth, Longini, Ira M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850009/
https://ncbi.nlm.nih.gov/pubmed/29020332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cix766
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