Organ-specific responses during brain death: increased aerobic metabolism in the liver and anaerobic metabolism with decreased perfusion in the kidneys

Hepatic and renal energy status prior to transplantation correlates with graft survival. However, effects of brain death (BD) on organ-specific energy status are largely unknown. We studied metabolism, perfusion, oxygen consumption, and mitochondrial function in the liver and kidneys following BD. B...

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Udgivet i:Sci Rep
Main Authors: Van Erp, A. C., Rebolledo, R. A., Hoeksma, D., Jespersen, N. R., Ottens, P. J., Nørregaard, R., Pedersen, M., Laustsen, C., Burgerhof, J. G. M., Wolters, J. C., Ciapaite, J., Bøtker, H. E., Leuvenink, H. G. D., Jespersen, B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849719/
https://ncbi.nlm.nih.gov/pubmed/29535334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22689-9
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