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Use of quercetin in animal feed: effects on the P-gp expression and pharmacokinetics of orally administrated enrofloxacin in chicken

Modulation of P-glycoprotein (P-gp, encoded by Mdr1) by xenobiotics plays central role in pharmacokinetics of various drugs. Quercetin has a potential to modulate P-gp in rodents, however, its effects on P-gp modulation in chicken are still unclear. Herein, study reports role of quercetin in modulat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bhutto, Zohaib Ahmed, He, Fang, Zloh, Mire, Yang, Jing, Huang, Jinhu, Guo, Tingting, Wang, Liping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849680/
https://ncbi.nlm.nih.gov/pubmed/29535328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22354-1
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