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Entropic trap purification of long DNA

Long-read genomic applications, such as genome mapping in nanochannels, require long DNA that is free of small-DNA impurities. We have developed a chip-based system based on entropic trapping that can simultaneously concentrate and purify a long DNA sample under the alternating application of an app...

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Detalles Bibliográficos
Publicado en:Lab Chip
Main Authors: Agrawal, Pranav, Bognár, Zsófia, Dorfman, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849573/
https://ncbi.nlm.nih.gov/pubmed/29469139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7lc01355h
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