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Detecting genetic association through shortest paths in a bi-directed graph

Genome-wide association studies (GWASs) commonly use marginal association tests for each single nucleotide polymorphism (SNP). Because these tests treat SNPs as independent, their power will be suboptimal for detecting SNPs hidden by linkage disequilibrium (LD). One way to improve power is to use a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genet Epidemiol
Hauptverfasser: Ueki, Masao, Kawasaki, Yoshinori, Tamiya, Gen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849262/
https://ncbi.nlm.nih.gov/pubmed/28626864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22051
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