Epigenetic modifications in hyperhomocysteinemia: potential role in diabetic retinopathy and age-related macular degeneration

To study Hyperhomocysteinemia (HHcy)-induced epigenetic modifications as potential mechanisms of blood retinal barrier (BRB) dysfunction, retinas isolated from three- week-old mice with elevated level of Homocysteine (Hcy) due to lack of the enzyme cystathionine β-synthase (cbs(–/–), cbs(+/–) and cb...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Elmasry, Khaled, Mohamed, Riyaz, Sharma, Isha, Elsherbiny, Nehal M., Liu, Yutao, Al-Shabrawey, Mohamed, Tawfik, Amany
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper: Gerotarget (Focus on Aging)
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849155/
https://ncbi.nlm.nih.gov/pubmed/29560091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24333
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