Whole-Genome Cardiac DNA Methylation Fingerprint and Gene Expression Analysis Provide New Insights in the Pathogenesis of Chronic Chagas Disease Cardiomyopathy

BACKGROUND: Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and affects 10 million people worldwide. Approximately 12000 deaths attributable to Chagas disease occur annually due to chronic Chagas disease cardiomyopathy (CCC), an inflammatory cardiomyopathy pres...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Laugier, Laurie, Frade, Amanda Farage, Ferreira, Frederico Moraes, Baron, Monique Andrade, Teixeira, Priscila Camillo, Cabantous, Sandrine, Ferreira, Ludmila Rodrigues Pinto, Louis, Laurence, Rigaud, Vagner Oliveira Carvalho, Gaiotto, Fabio Antônio, Bacal, Fernando, Pomerantzeff, Pablo, Bocchi, Edimar, Kalil, Jorge, Santos, Ronaldo Honorato Barros, Cunha-Neto, Edecio, Chevillard, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Articles and Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849099/
https://ncbi.nlm.nih.gov/pubmed/28575239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cix506
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