Sputum or blood eosinophil association with clinical measures of COPD severity in the SPIROMICS cohort

BACKGROUND: Eosinophils in blood and sputum in chronic obstructive pulmonary disease (COPD) have been associated with more frequent exacerbations, lower lung function, and corticosteroid responsiveness. We hypothesized increased eosinophils are associated with a severe COPD phenotype, including exac...

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Detalhes bibliográficos
Publicado no:Lancet Respir Med
Principais autores: Hastie, AT, Martinez, FJ, Curtis, JL, Doerschuk, CM, Hansel, NN, Christenson, S, Putcha, N, Ortega, VE, Li, X, Barr, RG, Carretta, EE, Couper, DJ, Cooper, CB, Hoffman, EA, Kanner, RE, Kleerup, E, O’Neal, WK, Paine, R, Peters, SP, Alexis, NE, Woodruff, PG, Han, MK, Meyers, DA, Bleecker, ER
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849066/
https://ncbi.nlm.nih.gov/pubmed/29146301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(17)30432-0
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