Sputum or blood eosinophil association with clinical measures of COPD severity in the SPIROMICS cohort

BACKGROUND: Eosinophils in blood and sputum in chronic obstructive pulmonary disease (COPD) have been associated with more frequent exacerbations, lower lung function, and corticosteroid responsiveness. We hypothesized increased eosinophils are associated with a severe COPD phenotype, including exac...

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發表在:Lancet Respir Med
Main Authors: Hastie, AT, Martinez, FJ, Curtis, JL, Doerschuk, CM, Hansel, NN, Christenson, S, Putcha, N, Ortega, VE, Li, X, Barr, RG, Carretta, EE, Couper, DJ, Cooper, CB, Hoffman, EA, Kanner, RE, Kleerup, E, O’Neal, WK, Paine, R, Peters, SP, Alexis, NE, Woodruff, PG, Han, MK, Meyers, DA, Bleecker, ER
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849066/
https://ncbi.nlm.nih.gov/pubmed/29146301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(17)30432-0
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