Sputum or blood eosinophil association with clinical measures of COPD severity in the SPIROMICS cohort

BACKGROUND: Eosinophils in blood and sputum in chronic obstructive pulmonary disease (COPD) have been associated with more frequent exacerbations, lower lung function, and corticosteroid responsiveness. We hypothesized increased eosinophils are associated with a severe COPD phenotype, including exac...

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Veröffentlicht in:Lancet Respir Med
Hauptverfasser: Hastie, AT, Martinez, FJ, Curtis, JL, Doerschuk, CM, Hansel, NN, Christenson, S, Putcha, N, Ortega, VE, Li, X, Barr, RG, Carretta, EE, Couper, DJ, Cooper, CB, Hoffman, EA, Kanner, RE, Kleerup, E, O’Neal, WK, Paine, R, Peters, SP, Alexis, NE, Woodruff, PG, Han, MK, Meyers, DA, Bleecker, ER
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849066/
https://ncbi.nlm.nih.gov/pubmed/29146301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-2600(17)30432-0
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