HLA-B*57 and IFNL4-Related Polymorphisms Are Associated With Protection Against HIV-1 Disease Progression in Controllers

BACKGROUND. Human immunodeficiency virus type 1 (HIV-1) controllers maintain HIV-1 viremia at low levels (normally <2000 HIV-RNA copies/mL) without antiretroviral treatment. However, some HIV-1 controllers have evidence of immunologic progression with marked CD4(+) T-cell decline. We investigated...

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Publicado no:Clin Infect Dis
Main Authors: Dominguez-Molina, Beatriz, Tarancon-Diez, Laura, Hua, Stephane, Abad-Molina, Cristina, Rodriguez-Gallego, Esther, Machmach, Kawthar, Vidal, Francesc, Tural, Cristina, Moreno, Santiago, Goñi, María José, Ramírez de Arellano, Elena, del Val, Margarita, Gonzalez-Escribano, María Francisca, Del Romero, Jorge, Rodriguez, Carmen, Capa, Laura, Viciana, Pompeyo, Alcamí, José, Yu, Xu G., Walker, Bruce D., Leal, Manuel, Lichterfeld, Mathias, Ruiz-Mateos, Ezequiel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849048/
https://ncbi.nlm.nih.gov/pubmed/27986689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciw833
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