Targeted deletion of a 170-kb cluster of LINE-1 repeats and implications for regional control

Approximately half the mammalian genome is composed of repetitive sequences, and accumulating evidence suggests that some may have an impact on genome function. Here, we characterized a large array class of repeats of long-interspersed elements (LINE-1). Although widely distributed in mammals, locat...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Soares, Miguel L., Edwards, Carol A., Dearden, Frances L., Ferrón, Sacri R., Curran, Scott, Corish, Jennifer A., Rancourt, Rebecca C., Allen, Sarah E., Charalambous, Marika, Ferguson-Smith, Malcolm A., Rens, Willem, Adams, David J., Ferguson-Smith, Anne C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848613/
https://ncbi.nlm.nih.gov/pubmed/29367313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.221366.117
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