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Vesicular glutamate release from central axons contributes to myelin damage

The axon myelin sheath is prone to injury associated with N-methyl-d-aspartate (NMDA)-type glutamate receptor activation but the source of glutamate in this context is unknown. Myelin damage results in permanent action potential loss and severe functional deficit in the white matter of the CNS, for...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Doyle, Sean, Hansen, Daniel Bloch, Vella, Jasmine, Bond, Peter, Harper, Glenn, Zammit, Christian, Valentino, Mario, Fern, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847599/
https://ncbi.nlm.nih.gov/pubmed/29531223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03427-1
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