Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide

Human leukocyte antigen (HLA)-I molecules generally bind short peptides (8–10 amino acids), although extended HLA-I restricted peptides (>10 amino acids) can be presented to T cells. However, the function of such extended HLA-I epitopes in tumour immunity, and how they would be recognised by T-ce...

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Publicado no:Nat Commun
Main Authors: Chan, Kok Fei, Gully, Benjamin S., Gras, Stephanie, Beringer, Dennis X., Kjer-Nielsen, Lars, Cebon, Jonathan, McCluskey, James, Chen, Weisan, Rossjohn, Jamie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847591/
https://ncbi.nlm.nih.gov/pubmed/29531227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03321-w
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