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Improved mass spectrometric detection of acidic peptides by variations in the functional group pK(a) values of reverse micelle extraction agents

Polymeric reverse micelles can be used to selectively extract peptides from complex mixtures via a two-phase extraction approach. In previous work, we have shown that the charge polarity of the hydrophilic functional group that is in the interior of the reverse micelle dictates the extraction select...

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Publicat a:Analyst
Autors principals: Zhao, Bo, Serrano, Mahalia A. C., Wang, Meizhe, Liu, Tianying, Gordon, Mallory R., Thayumanavan, S., Vachet, Richard W.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847484/
https://ncbi.nlm.nih.gov/pubmed/29468243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7an02094e
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