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Electronic medical records can be used to emulate target trials of sustained treatment strategies
OBJECTIVE: To emulate three target trials: single treatment versus no treatment, joint treatment versus no treatment, and head-to-head comparison of two treatments. We explain how to estimate the observational analogs of intention-to-treat and per-protocol effects, using hazard ratios and survival c...
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| Publié dans: | J Clin Epidemiol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5847447/ https://ncbi.nlm.nih.gov/pubmed/29203418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2017.11.021 |
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