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Histological transformation of adenocarcinoma to small cell carcinoma lung as a rare mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors: Report of a case with review of literature

A subset of non-small cell lung carcinoma (NSCC) harbor active mutations of epidermal growth factor receptor (EGFR). In these, EGFR tyrosine kinase inhibitors (EGFR-TKIs) are recommended as the first-line treatment. Though drug resistance is inevitable, histological transformation to small cell lung...

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發表在:Lung India
Main Authors: Hui, Monalisa, Uppin, Shantveer G, Stalin, Bala Joseph, Sadashivudu, G
格式: Artigo
語言:Inglês
出版: Medknow Publications & Media Pvt Ltd 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846268/
https://ncbi.nlm.nih.gov/pubmed/29487254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/lungindia.lungindia_347_17
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