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Fibroblast growth factor 2 induces proliferation and fibrosis via SNAI1-mediated activation of CDK2 and ZEB1 in corneal endothelium

Investigating stimulation of endogenous wound healing in corneal endothelial cells (CECs) may help address the global shortage of donor corneas by decreasing the number of transplants performed for blindness because of endothelial dysfunction. We previously reported that IL-1β stimulation leads to f...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Lee, Jeong Goo, Jung, Eric, Heur, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846169/
https://ncbi.nlm.nih.gov/pubmed/29363574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000295
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