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Computational antimicrobial peptide design and evaluation against multidrug-resistant clinical isolates of bacteria
There is a pressing need for new therapeutics to combat multidrug- and carbapenem-resistant bacterial pathogens. This challenge prompted us to use a long short-term memory (LSTM) language model to understand the underlying grammar, i.e. the arrangement and frequencies of amino acid residues, in know...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846155/ https://ncbi.nlm.nih.gov/pubmed/29259134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.805499 |
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