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Controlled dimerization of insulin-like growth factor-1 and insulin receptors reveals shared and distinct activities of holo and hybrid receptors

Breast cancer development and progression are influenced by insulin-like growth factor receptor 1 (IGF1R) and insulin receptor (InsR) signaling, which drive cancer phenotypes such as cell growth, proliferation, and migration. IGF1R and InsR form IGF1R/InsR hybrid receptors (HybRs) consisting of one...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Chen, Jingci, Nagle, Alison M., Wang, Yu-Fen, Boone, David N., Lee, Adrian V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846141/
https://ncbi.nlm.nih.gov/pubmed/29330302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.789503
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