KRAS mutations in cell-free DNA from preoperative and postoperative sera as a pancreatic cancer marker: a retrospective study

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) has very poor prognosis despite existing multimodal therapies. This study aimed to investigate whether KRAS mutations at codons 12/13 in cell-free DNA (cfDNA) from preoperative and postoperative sera from patients with PDAC can serve as a predictiv...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Nakano, Yutaka, Kitago, Minoru, Matsuda, Sachiko, Nakamura, Yuki, Fujita, Yusuke, Imai, Shunichi, Shinoda, Masahiro, Yagi, Hiroshi, Abe, Yuta, Hibi, Taizo, Fujii-Nishimura, Yoko, Takeuchi, Ayano, Endo, Yutaka, Itano, Osamu, Kitagawa, Yuko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846073/
https://ncbi.nlm.nih.gov/pubmed/29360815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.479
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