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Mapping of Thalamic Magnetic Susceptibility in Multiple Sclerosis Indicates Decreasing Iron with Disease Duration: A Proposed Mechanistic Relationship between Inflammation and Oligodendrocyte Vitality

Recent advances in susceptibility MRI have dramatically improved the visualization of deep gray matter brain regions and the quantification of their magnetic properties in vivo, providing a novel tool to study the poorly understood iron homeostasis in the human brain. In this study, we used an advan...

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Bibliographische Detailangaben
Veröffentlicht in:Neuroimage
Hauptverfasser: Schweser, Ferdinand, Martins, Ana Luiza Raffaini Duarte, Hagemeier, Jesper, Lin, Fuchun, Hanspach, Jannis, Weinstock-Guttman, Bianca, Hametner, Simon, Bergsland, Niels P., Dwyer, Michael G., Zivadinov, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845810/
https://ncbi.nlm.nih.gov/pubmed/29097315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2017.10.063
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