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Lysophosphatidic acid regulates the motility of MCF10CA1a breast cancer cell sheets via two opposing signaling pathways

Aberrant cell migration leads to the dispersal of malignant cells. The ubiquitous lipid mediator lysophosphatidic acid (LPA) modulates cell migration and is implicated in tumor progression. Yet, the signaling cascades that regulate LPA’s effect on cell motility remain unclear. Using time-lapse imagi...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Stuelten, Christina H., Lee, Rachel M., Losert, Wolfgang, Parent, Carole A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845779/
https://ncbi.nlm.nih.gov/pubmed/29337044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.01.005
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