Human Body Composition and Immunity: Visceral Adipose Tissue Produces IL-15 and Muscle Strength Inversely Correlates with NK Cell Function in Elderly Humans

Natural killer (NK) lymphocyte-mediated cytotoxicity and cytokine secretion control infections and cancers, but these crucial activities decline with age. NK cell development, homeostasis, and function require IL-15 and its chaperone, IL-15 receptor alpha (IL-15Rα). Macrophages and dendritic cells (...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Al-Attar, Ahmad, Presnell, Steven R., Clasey, Jody L., Long, Douglas E., Walton, R. Grace, Sexton, Morgan, Starr, Marlene E., Kern, Philip A., Peterson, Charlotte A., Lutz, Charles T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845694/
https://ncbi.nlm.nih.gov/pubmed/29559978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00440
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