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Altered Function and Expression of ABC Transporters at the Blood–Brain Barrier and Increased Brain Distribution of Phenobarbital in Acute Liver Failure Mice

This study investigated alterations in the function and expression of P-glycoprotein (P-GP), breast cancer resistance protein (BCRP), and multidrug resistance-associated protein 2 (MRP2) at the blood–brain barrier (BBB) of acute liver failure (ALF) mice and its clinical significance. ALF mice were d...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Liu, Li, Miao, Mingxing, Chen, Yang, Wang, Zhongjian, Sun, Binbin, Liu, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845647/
https://ncbi.nlm.nih.gov/pubmed/29559914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00190
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