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Heritability and Genome-Wide Association Analyses of Serum Uric Acid in Middle and Old-Aged Chinese Twins

Serum uric acid (SUA), as the end product of purine metabolism, has proven emerging roles in human disorders. Here based on a sample of 379 middle and old-aged Chinese twin pairs, we aimed to explore the magnitude of genetic impact on SUA variation by performing sex-limitation twin modeling analyses...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Wang, Weijing, Zhang, Dongfeng, Xu, Chunsheng, Wu, Yili, Duan, Haiping, Li, Shuxia, Tan, Qihua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845532/
https://ncbi.nlm.nih.gov/pubmed/29559957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00075
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