Fisetin Confers Cardioprotection against Myocardial Ischemia Reperfusion Injury by Suppressing Mitochondrial Oxidative Stress and Mitochondrial Dysfunction and Inhibiting Glycogen Synthase Kinase 3β Activity

Acute myocardial infarction (AMI) is the leading cause of morbidity and mortality worldwide. Timely reperfusion is considered an optimal treatment for AMI. Paradoxically, the procedure of reperfusion can itself cause myocardial tissue injury. Therefore, a strategy to minimize the reperfusion-induced...

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Bibliographische Detailangaben
Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Shanmugam, Karthi, Ravindran, Sriram, Kurian, Gino A., Rajesh, Mohanraj
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845518/
https://ncbi.nlm.nih.gov/pubmed/29636855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9173436
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