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Exosomes associated with human ovarian tumors harbor a reversible checkpoint of T cell responses

Nano-sized membrane-encapsulated extracellular vesicles isolated from the ascites fluids of ovarian cancer patients are identified as exosomes based on their biophysical and compositional characteristics. We report here that T cells pulsed with these tumor-associated exosomes during TCR-dependent ac...

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Publicat a:Cancer Immunol Res
Autors principals: Shenoy, Gautam N., Loyall, Jenni, Maguire, Orla, Iyer, Vandana, Kelleher, Raymond J., Minderman, Hans, Wallace, Paul K., Odunsi, Kunle, Balu-Iyer, Sathy V., Bankert, Richard B.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845437/
https://ncbi.nlm.nih.gov/pubmed/29301753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-17-0113
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