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Epigenetic regulation of cancer progression by EZH2: from biological insights to therapeutic potential
Enhancer of zeste homolog 2 (EZH2), a histone methyltransferase and a catalytic component of PRC2, catalyzes tri-methylation of histone H3 at Lys 27 (H3K27me3) to regulate gene expression through epigenetic machinery. EZH2 also functions both as a transcriptional suppressor and a transcriptional co-...
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| 出版年: | Biomark Res |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5845366/ https://ncbi.nlm.nih.gov/pubmed/29556394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-018-0122-2 |
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