Antibody levels to recombinant VAR2CSA domains vary with Plasmodium falciparum parasitaemia, gestational age, and gravidity, but do not predict pregnancy outcomes

BACKGROUND: Maternal malaria is a tropical scourge associated with poor pregnancy outcomes. Women become resistant to Plasmodium falciparum pregnancy malaria as they acquire antibodies to the variant surface antigen VAR2CSA, a leading vaccine candidate. Because malaria infection may increase VAR2CSA...

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Bibliographic Details
Published in:Malar J
Main Authors: Fried, Michal, Kurtis, Jonathan D., Swihart, Bruce, Morrison, Robert, Pond-Tor, Sunthorn, Barry, Amadou, Sidibe, Youssoufa, Keita, Sekouba, Mahamar, Almahamoudou, Andemel, Naissem, Attaher, Oumar, Dembele, Adama B., Cisse, Kadidia B., Diarra, Bacary S., Kanoute, Moussa B., Narum, David L., Dicko, Alassane, Duffy, Patrick E.
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845157/
https://ncbi.nlm.nih.gov/pubmed/29523137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2258-9
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